The opinion in support of the decision being entered today was not written for publication and is not binding precedent of the Board. Paper No. 52 UNITED STATES PATENT AND TRADEMARK OFFICE __________ BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES __________ Ex parte XANDRA O. BREAKEFIELD, and ROBERT L. MARTUZA __________ Appeal No. 2001-1686 Application No. 08/363,998 __________ HEARD: February 7, 2002 __________ Before WINTERS, WILLIAM F. SMITH, and GREEN, Administrative Patent Judges. GREEN, Administrative Patent Judge. DECISION ON APPEAL This is a decision on appeal under 35 U.S.C. § 134 from the examiner’s final rejection of claims 54, 55, 57, 59-61 and 72-77. Claim 54 is representative of the subject matter on appeal, and reads as follows: 54. A method of expressing a gene sequence in a neuronal cell of the central nervous system, said method comprising: directly administering into said neuronal cell a herpes simplex virus 1 (HSV-1) mutant as a vector for gene delivery, said HSV-1 mutant comprising: (a) a deletion in an immediate early gene whereby said deletion in an immediate early gene is replaced byPage: 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007