Ex Parte CUFF et al - Page 4



              Appeal No. 2001-2157                                                               Page 4                
              Application No. 08/918,741                                                                               




















                                              The Prior Art References                                                 
                     In rejecting the appealed claims under 35 U.S.C. § 103(a), the examiner relies                    
              on the following prior art references:                                                                   
              Jones et al. (Jones)                     4,358,593            Nov.   9, 1982                             
              Ronsen et al. (Ronsen)                   5,672,612            Sep. 30, 1997                              
              Cameron (PCT Application)                WO 95/10513          Apr. 20, 1995                              

              Evans, "An Introduction to Crystal Chemistry," 2nd edition, pp. 393-397 (Cambridge                       
              Press 1964)                                                                                              
              Hannay, "Treatise on Solid State Chemistry," Vol. 3,  pp. 89-90 (Plenum Press 1977)                      
              Kai et al. (Kai), "Oral Absorption Improvement of Poorly Soluble Drug Using Solid                        
              Dispersion Technique," Chem. Pharm. Bull., Vol. 44, no. 3, pp. 568-571 (1996)                            

              Matsuda et al. (Matsuda), "Amorphism and Physiochemical Stability of Spray-dried                         





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