Ex Parte CUFF et al - Page 10



                  Appeal No. 2001-2157                                                                                      Page 10                       
                  Application No. 08/918,741                                                                                                              
                  we point out that "[w]here a reference is relied on to support a rejection, whether or not                                              
                  in a 'minor capacity,' there would appear to be no excuse for not positively including the                                              
                  reference in the statement of rejection."  In re Hoch, 428 F.2d 1341, 1342 n.3, 166                                                     
                  USPQ 406, 407 n.3 (CCPA 1970).  The examiner has not included the Concise                                                               
                  Encyclopedia Chemistry in a statement of any rejection under 35 U.S.C. § 103(a), and                                                    
                  belated citation of that reference in Paper No. 13, page 5, is improper.  Be that as it                                                 
                  may, we have reviewed the Concise Encyclopedia Chemistry, page 67.  In our                                                              
                  judgment, this reference does not disclose that spray-drying was known for preparing                                                    
                  products structurally similar to raloxifene.  Nor does this reference refute applicants'                                                
                  contention that, at most, it would have been obvious to try preparing raloxifene in an                                                  
                  amorphous form by spray-drying.                                                                                                         


                                                                     Conclusion                                                                           
                           In conclusion, the examiner has not established that the prior art would have led                                              
                  a person having ordinary skill to the claimed invention with a reasonable expectation of                                                
                  success.  Accordingly, the examiner has not established a prima facie case of                                                           


                  obviousness of claims 1 and 3 through 10; and the examiner's decision rejecting those                                                   
                  claims under 35 U.S.C. § 103(a) is reversed.                                                                                            
                                                                    REVERSED                                                                              


                                                                                          )                                                               
                                                      Sherman D. Winters                           )                                                      
                                                      Administrative Patent Judge                  )                                                      





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