Ex Parte BERG - Page 5



              Appeal No. 2002-0456                                                                   Page 5                 
              Application No. 09/155,995                                                                                    
              results of cross-linking Sepharose ® with allylbromide.  According to the examiner’s                          
              argument, then, the Sepharose ® used in the example is not a gel.  As this would be                           
              inconsistent with Lindgren’s generic description of the prior art process (not to mention                     
              Examples 2 through 6), and as the examiner has provided no factual basis for his                              
              assertion, we are not persuaded by this argument.  Similarly, the examiner has not                            
              established a factual basis for his assertion that “the product produced by the prior art                     
              method is . . . patentably indistinguishable from the instant claimed product” (Answer,                       
              page 4).                                                                                                      
                     Finally, we are at a loss as to how the examiner can interpret “[a]ppellant’s                          
              admission . . . that the contacting of agarose or other polysacharides with crosslinking                      
              agents is conventional in the art” as “an admission that . . . the appropriate conditions                     
              for their use are not a patentably distinguishing feature.”  Answer, page 6.                                  
                     The initial burden of presenting a prima facie case of obviousness rests on the                        
              examiner.  In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d 1443, 1444 (Fed. Cir.                                
              1992).  Thus, the examiner is charged with adequately addressing every limitation of                          
              the claimed invention.  This the examiner has not done.  In our judgment, Lindgren’s                          
              disclosure, with or without “appellant’s admission,”  is insufficient to support a                            
              conclusion of obviousness of claims containing the limitations discussed above and the                        
              examiner has failed to provide an adequate factual basis to establish a prima facie case                      
              of obviousness within the meaning of 35 U.S.C. § 103.                                                         











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