Ex Parte Murugesan et al - Page 1




                         The opinion in support of the decision being entered today was not written           
                                for publication and is not binding precedent of the Board.                    
                                                                                 Paper No. 12                 
                      UNITED STATES PATENT AND TRADEMARK OFFICE                                               
                                                __________                                                    
                            BEFORE THE BOARD OF PATENT APPEALS                                                
                                         AND INTERFERENCES                                                    
                                                __________                                                    
                              Ex parte NATESAN MURUGESAN, JOHN T. HUNT                                        
                                            and PHILIP D. STEIN                                               
                                                __________                                                    
                                            Appeal No. 2002-0522                                              
                                          Application No. 09/552,543                                          
                                                __________                                                    
                                                 ON BRIEF                                                     
                                                __________                                                    
                Before WINTERS, WILLIAM F. SMITH, and GRIMES, Administrative Patent                           
                Judges.                                                                                       
                GRIMES, Administrative Patent Judge.                                                          

                                           DECISION ON APPEAL                                                 
                      This is a decision on appeal under 35 U.S.C. § 134 from the examiner’s                  
                final rejection of claims 23, 24, 26, and 27.  Claims 25 and 28 are also pending;             
                the examiner has indicated that these claims would be allowable if rewritten in               
                independent form.  See Paper No. 3, mailed October 2, 2000, page 3.                           
                      Claim 23 is representative and reads as follows:                                        
                      23. A pharmaceutical composition comprising at least one endothelin                     
                antagonist in combination with at least one additional therapeutic agent selected             
                from ECE inhibitors, PAF antagonists, AII receptor antagonists, renin inhibitors,             
                ACE inhibitors, NEP inhibitors, HMG CoA reductase inhibitors, squalene                        
                synthetase inhibitors, bile acid sequestrants, calcium channel blockers,                      






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