Ex Parte Murugesan et al - Page 5


                Appeal No. 2002-0522                                                  Page 5                  
                Application No. 09/552,543                                                                    

                      Appellants argue that “[t]he skilled artisan reading Applicant’s [sic] parent           
                specification would clearly and naturally understand that the disclosure at page              
                10, lines 4-34 is generally applicable to endothelin antagonists as an entire                 
                class—not just the specific endothelin antagonists of formula I.”  Appeal Brief,              
                page 3.  Appellants cite In re Smythe, 480 F.2d 1376, 178 USPQ 279 (CCPA                      
                1973), as supporting their position.                                                          
                      This argument is not convincing.  Again, the specification describes only               
                compositions comprising the endothelin antagonists of formula I.  Appellants                  
                have pointed to nothing in the specification that would have led those skilled in             
                the art to conclude that Appellants invented compositions comprising endothelin               
                antagonists other than those of formula I.  See Lockwood, 107 F.3d at 1572, 41                
                USPQ2d at 1966 (“One shows that one is ‘in possession’ of the invention by                    
                describing the invention, with all its claimed limitations, not that which makes it           
                obvious.”).                                                                                   
                      In re Smythe does not support Appellants’ position.  In Smythe, the                     
                specification disclosed a process comprising, inter alia, a “segmentizing medium”             
                that was “air or other gas which is inert to [a] liquid.”  480 F.2d at 1384,                  
                178 USPQ at 280.  The claimed process, by contrast, recited the segmentizing                  
                medium as “an inert fluid immiscible with said liquid samples.”  See id.  The court           
                reversed the rejection for inadequate written description, even though the claim              
                term “fluid” was broader than the specification’s “air or other gas,” because “the            
                specification clearly conveys to one skilled in the art that in this invention the            







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