Ex Parte FRITZ - Page 9


                 Appeal No. 2002-0534                                                         Page 9                   
                 Application No. 08/551,326                                                                            

                 requires the oft-difficult but critical step of casting the mind back to the time of                  
                 invention, to consider the thinking of one of ordinary skill in the art, guided only                  
                 by the prior art references and the then-accepted wisdom in the field.”).                             
                        Thus, we agree with Appellant that the references cited by the examiner                        
                 would not have suggested combining the specific elements of the claimed                               
                 products and methods, in the manner recited in the claims.  The references                            
                 therefore do not support a prima facie case of obviousness.  The rejection under                      
                 35 U.S.C. § 103 is reversed.                                                                          
                                                    Other Issues                                                       
                        As Appellant points out (Appeal Brief, pages 15-16), Monteleone 19922                          
                 appears to be closer prior art than the Monteleone reference applied by the                           
                 examiner.  Monteleone 1992 discloses administration of bovine cortex-derived                          
                 phosphatidylserine to human subjects and measurement of the effect on, inter                          
                 alia, cortisol levels after exercise.  Monteleone 1992 concludes that “chronic oral                   
                 administration of phosphatidylserine may counteract stress-induced activation of                      
                 the hypothalamo-pituitary-adrenal axis in man.”  Abstract.                                            
                        Claim 25 in the instant application is directed to a “method for optimizing                    
                 muscle development during intense physical exercise which comprises ingesting                         
                 an anti-catabolic nutrient, soy derived phosphatidylserine, in an amount that                         
                 suppresses elevation in the level of cortisol release during the physical exercise.”                  
                 Monteleone 1992 appears to meet all the express limitations of this claim except                      
                                                                                                                       
                 2 Monteleone et al., “Blunting by chronic phosphatidylserine administration of the stress-induced     
                 activation of the hypothalamo-pituitary-adrenal axis in healthy men,” Eur. J. Clin. Pharmacol., Vol.  
                 42, pp. 385-388 (1992), of record.                                                                    





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