Ex Parte GEESIN et al - Page 1



                               The opinion in support of the decision being entered today was not written                               
                                        for publication and is not binding precedent of the Board.                                      

                                                                                                        Paper No. 29                    

                            UNITED STATES PATENT AND TRADEMARK OFFICE                                                                   
                                                           __________                                                                   

                                  BEFORE THE BOARD OF PATENT APPEALS                                                                    
                                                   AND INTERFERENCES                                                                    
                                                            __________                                                                  
                                              Ex parte JEFFREY C. GEESIN and                                                            
                                                       ANNA GOSIEWSKA                                                                   
                                                           ___________                                                                  
                                                      Appeal No. 2002-1296                                                              
                                                   Application No. 08/957,038                                                           
                                                            __________                                                                  
                                                             ON BRIEF                                                                   
                                                            __________                                                                  
                Before WILLIAM F. SMITH, SCHEINER, and GRIMES,  Administrative Patent Judges.                                           
                WILLIAM F. SMITH, Administrative Patent Judge.                                                                          
                                                     DECISION ON APPEAL                                                                 
                        This is an appeal under 35 U.S.C. § 134 from the final rejection of claims 15                                   
                through 21, all the claims remaining in the application.  Claim 15 is representative of the                             
                subject matter on appeal and reads as follows:                                                                          
                        15.  A method for identifying modulators of scar formation, comprising the steps                                
                of:                                                                                                                     
                        (a)    incubating immortalized, non-cancerous macrophages with an exogenous                                     
                               source of latent TGF-$1 and a modulator compound that modulates latent                                   
                               TGF-$1 activation;                                                                                       
                        (b)    measuring the amount of active TGF-$1 produced by the macrophages;                                       
                               and                                                                                                      







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