Ex Parte HORWITZ - Page 14




               Appeal No. 2002-1740                                                                                                 
               Application No. 08/447,398                                                                                           

                       Appellant has come forth with no evidence to support his position that there                                 
               would not have been a reasonable expectation of success on the part of one of ordinary                               
               skill in the art of obtaining a vaccine providing a protective immune response.  Nor has                             
               appellant put forth any other argument or reasoning which would suggest that the                                     
               examiner has not properly established a prima facie case of obviousness.   To this end                               
               we note arguments of counsel cannot take the place of evidence.  In re DeBlauwe, 736                                 
               F.2d 699, 705, 222 USPQ 191, 196 (Fed. Cir. 1984), In re Payne, 606 F.2d 303, 315,                                   
               203 USPQ 245, 256 (CCPA 1979).                                                                                       
                       We do not further address the disclosures of Salata, Wallis, Zhang, Munk and                                 
               Verbon, as we find the combination of Pal and Borremans renders the invention of                                     
               claim 47 obvious.   Additional claims stand or fall with claim 47.   The other references                            
               relied upon by the examiner address limitations in the dependent claims which have not                               
               been separately argued by appellant.   We do not comment further upon these                                          
               references as they are not necessary to support rejection of claim 47.                                               
                       We find the examiner has established a prima facie case of obviousness which                                 
               has not been rebutted by appellant with appropriate argument or evidence.  The                                       
               rejection of the claims for obviousness is affirmed.                                                                 







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