Ex Parte HAIK - Page 3


                    Appeal No.  2002-1874                                                                     Page 3                        
                    Application No.  09/079,329                                                                                             

                    claim the subject matter that applicant regards as the invention.  Claims 47-49,                                        
                    54,56, 237-244 stand rejected under 35 U.S.C. § 103(a) as obvious over                                                  
                    Selwood or Lo as combined with the admitted prior art, and claims 47-49, 54-56                                          
                    and 237-244 stand rejected under 35 U.S.C. § 103(a) as being obvious over the                                           
                    combination of Khaidar and Lo.  After careful review of the record and                                                  
                    consideration of the issues before us, we reverse all of the rejections of record.                                      
                                                             DISCUSSION                                                                     
                    1.      35 U.S.C. § 112, First Paragraph, Enablement                                                                    
                            Claims 47-49, 54-57 and 237-240 stand rejected under 35 U.S.C. § 112,                                           
                    first paragraph, on the grounds that the specification does not enable any person                                       
                    skilled in the art to which it pertains, or with which it is most nearly connected, to                                  
                    make and/or use the invention commensurate in scope with the claims.                                                    
                            The rejection asserts that the specification only illustrates the effects of                                    
                    arginine on methylglyoxal, while the claim reads on any carbonyl compound “as                                           
                    the term ‘toxic’ does not define any specific structure or origin of the carbonyl                                       
                    compounds being blocked.”  Examiner’s Answer, page 5.  The rejection                                                    
                    contends further that there are no examples presented by the specification of                                           
                    blocking other carbonyl containing compounds, and that the disclosure provides                                          
                    no guidance as to what other compounds may be blocked and under what                                                    
                    conditions.  See id.                                                                                                    
                            The rejection cites Lo and Selwood for their teachings of the blocking of                                       
                    methylglyoxal, and also cites Khaidar for is teaching of the possible interaction of                                    
                    arginine and carbonyl compounds involved in collagen cross-linking.  But then                                           





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