Appeal No. 2002-1916 Application 09/332,772 guidewire and dilator (93) are removed so that catheters or other medical devices can then be passed through the lumen of the catheter member (20) into the desired vessel. Thus, the adapter (93) need not be positioned within the lumen of catheter member (20) at all times and the user clearly has the option of removing it or not when appropriate. We are also of the view that a further guidewire of a size on the order of the outside diameter of adapter (93) or smaller would reasonably fall within the bounds of “other medical devices” to be passed through the catheter member (20) and into the blood vessel as mentioned in Donadio (col. 3, lines 5-7). Contrary to appellants’ arguments in their brief (pages 8-9) and reply brief (page 3), we consider that Donadio clearly discloses a catheter member (20) having a lumen which is capable of accommodating a first guidewire having an external diameter of a given size and also guidewires of different diameters, wherein the guidewire diameters may fall within a range slightly smaller than the outer diameter of adapter (93) to just larger than the outer diameter of the guidewire (95). 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007