Ex Parte Clement et al - Page 5



                    Appeal No. 2003-0124                                                                                                                                  
                    Application No. 09/487,832                                                                                                                            

                    enablement requirement is found in Section 112, Para. 1, which                                                                                        
                    provides in relevant part that:                                                                                                                       
                              The specification shall contain a written description                                                                                       
                              of the invention, and of the manner and process of                                                                                          
                              making and using it, in such full, clear, concise, and                                                                                      
                              exact terms as to enable any person skilled in the art                                                                                      
                              to which it pertains, or with which it is most nearly                                                                                       
                              connected, to make and use the same . . . .                                                                                                 
                    35 U.S.C. § 112, Para. 1 (1994)."  "To be enabling, the                                                                                               
                    specification of a patent must teach those skilled in the art how                                                                                     
                    to make and use the full scope of the claimed invention without                                                                                       
                    'undue experimentation'."  Genentech, Inc. v. Novo Nordisk, A/S                                                                                       
                    108 F.3d 1361, 1365, 42 USPQ2d 1001, 1004 (Fed. Cir. 1997)                                                                                            
                    (quoting In re Wright, 999 F.2d 1557, 1561, 27 USPQ2d 1510, 1513                                                                                      
                    (Fed. Cir. 1993)).  Whether claims are sufficiently enabled by a                                                                                      
                    disclosure in a specification is determined as of the date that                                                                                       
                    the patent application was first filed, see Hybritech, Inc. v.                                                                                        
                    Monoclonal Antibodies, Inc., 802 F.2d 1367, 1384, 231 USPQ 81, 94                                                                                     
                    (Fed. Cir. 1986),. . .  Our reviewing court has held that a                                                                                           
                    patent specification complies with the statute even if a                                                                                              
                    "reasonable" amount of routine experimentation is required in                                                                                         
                    order to practice a claimed invention, but that such                                                                                                  
                    experimentation must not be  "undue."  See, e.g., In re Wands,                                                                                        

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