Appeal No. 2003-0869 Application No. 09/692,715 In order to establish a prima facie case of obviousness, there must be either some suggestion or motivation to modify the references or combine reference teachings and a reasonable expectation of success. In re Vaeck, 947 F.2d 488, 493, 20 USPQ2d 1438, 1442 (Fed. Cir. 1991). In the absence of a reasonable expectation of success, one is left with only an “obvious to try” situation which is not the standard of obviousness under 35 U.S.C. § 103. See In re O’Farrell, 858 F.2d 894, 903, 7 USPQ2d 1673, 1680 (Fed. Cir. 1988). Absent some evidence that Audousset’s oxidation bases (e.g., the pyrimidine oxidation bases) would have been expected to function with a reasonable expectation of success with Ogawa’s coupler system, we cannot agree that a prima facie case of obviousness has been established. Accordingly, we must reverse this rejection. The Rejection of Claims 61 and 62 under 35 U.S.C. § 103(a) As this rejection relies upon the combination of Ogawa and Audousset, we reverse this rejection for the reasons discussed above. The Rejection of Claim 63 under 35 U.S.C. § 103(a) 7Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007