The opinion in support of the decision being entered today was not written
for publication and is not binding precedent of the Board.
Paper No. 18
UNITED STATES PATENT AND TRADEMARK OFFICE
__________
BEFORE THE BOARD OF PATENT APPEALS
AND INTERFERENCES
__________
Ex parte ALONSO CASTRO
__________
Appeal No. 2003-0892
Application No. 09/454,3851
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ON BRIEF
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Before SCHEINER, ADAMS and GREEN, Administrative Patent Judges.
SCHEINER, Administrative Patent Judge.
DECISION ON APPEAL
This is an appeal under 35 U.S.C. § 134 from the final rejection of claims 1-12,
all of the claims in the application.
Claim 1, the sole independent claim, is representative:
1. A method for identifying single molecules having a target DNA or RNA
sequence comprising the steps of:
selecting a primer having a 3'-hydroxyl group at one end and having a sequence
of nucleotides to specifically hybridize with an identifying sequence of nucleotides in the
target DNA;
hybridizing the primer to the identifying nucleotide sequences of the target DNA
or RNA sequence;
extending the primer along the target sequence by progressively binding a
plurality of nucleotides to the primer that are complementary to the corresponding
nucleotides on the target sequence to form a reporter molecule, where the
complementary nucleotides include nucleotides labeled with a fluorophore; and
detecting fluorescence emitted by fluorophores on individual reporter molecules
by a process selected from the group consisting of flow cytometry and single molecule
1 Application for patent filed December 3, 1999. According to appellant, this
application claims the benefit of provisional application serial no. 60/113,139, filed
December 18, 1998.
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