Ex Parte ZIMMERMANN et al - Page 9



              Appeal No. 2003-0919                                                                   Page 9                 
              Application No. 09/463,097                                                                                    
                     Second, the principle of law enunciated in Ex parte Hartop, 139 USPQ 525 (Bd.                          
              App. 1962) has been substantially discredited in In re Cofer, 354 F.2d 664, 667-68, 148                       
              USPQ 268, 270-71 (CCPA 1966).                                                                                 
                     Third, on this record, the examiner has not adequately explained how a person                          
              having ordinary skill would have been led from "here to there," i.e., from the                                
              methanesulfonic acid addition salt of imatinib to the non-hygroscopic or $-crystalline                        
              form of that compound recited in the appealed claims.                                                         
                     The rejection under 35 U.S.C. § 103(a) is reversed.                                                    


                                                        Conclusion                                                          
                     In conclusion, for the reasons set forth, we do not sustain the examiner's                             
              rejections 35 U.S.C. § 112, second paragraph; 35 U.S.C. § 112, first paragraph;                               
              35 U.S.C. § 102(b); or 35 U.S.C. § 103(a).                                                                    























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