Ex Parte STACHE et al - Page 6


                Appeal No. 2003-1034                                                  Page 6                 
                Application No. 08/897,455                                                                   

                compounds have a 21-ester substituent and that Page teaches that when R5 is                  
                RCOO, R is one of three groups, an alkyl group, an aralkyl group or a phenyl                 
                group.  However, as Page exemplifies only sixteen esters, and as none of the                 
                thirty-three compounds exemplified by Page has a phenyl substituent in the 21                
                position, the reference does not direct one of ordinary skill in the art to the use of       
                the aralkyl group.                                                                           
                      Finally, with respect to the rejection over Bowers and the rejection over              
                Oughton, the examiner again concludes:                                                       
                      [I]t would have been obvious to one having ordinary skill in the art                   
                      at the time of the present application to select any of the species of                 
                      the genus taught by the reference including those of the instant                       
                      claims, because he would have the reasonable expectation that                          
                      any of the species of the genus would have similar properties, and                     
                      thus, the same use as the genus as a whole.  The motivation to                         
                      make the claimed compounds is based on the desire to make                              
                      additional compounds useful as taught by the prior art.                                
                Examiner’s Answer, pages 5-6.  Thus, the rejection over Bowers and the                       
                rejection over Oughton are vacated for the same reasons as set forth above.                  
                                         FUTURE PROCEEDINGS                                                  
                      Upon remand, the examiner should address the patentability of the claims               
                in accordance with this opinion.  The patentability of the pending claims should             
                be addressed in view of the Djerassi reference, as discussed above, and any                  
                other reference that the examiner may feel is relevant to the patentability of the           
                claim.  If a rejection is made under 35 U.S.C. § 103, we suggest the examiner                
                adhere to the model set forth in The Manual of Patent Examining Procedure                    
                (MPEP) § 706.02(j).  Use of that model will ensure that the examiner perform the             






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