Interference No. 104,522 Paper`108 Nichols v. Tabakoff Page 36 considered synthesis of 4-urea kynurenic acid derivatives within or beyond ordinary skill in the art. 13 Nichols did not offer any independent testimony by one of ordinary skill in the art sharing Dr. Nichols'opinion that undue or extensive research was required to synthesize 4-urea kynurenate derivatives. Nichols has not pointed to, and we do not find, evidence that Dr. Nichols had to undertake extensive literature searches, scientific consultations, etc. as to possible synthesis routes. 74. To the contrary, Dr. Nichols admitted that Dr. Snell sent him papers on synthesizing similar types of prior art compounds (NR, p. 72,1. 23 - p. 73,1. 22). 75. Moreover, according to James A. Ruth, a Ph.D. in synthetic organic chemistry who testified on behalf of Tabakoff, an ordinary organic chemist would have known how to synthesize a 4-urea kynurenic acid, e.g., 13 The Declaration of Dr. K. Lemone Yielding (Ex 2001; NR, pp. 1-2) is confined to authenticating six letters (Exs 2003-2007) he received from Dr. Tabakoff.Page: Previous 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 NextLast modified: November 3, 2007