LAUDANO et al v. DANA-FARBER - Page 2




                Interference No. 104,717                                                                       Paper 30                  
                Laudano v. Dana-Farber Cancer Inst., Inc.                                                        Page 2                  
                                                                FACTS                                                                    
                        The following facts are supported by at least a preponderance of the evidence:                                   
        [1]     There are three counts in the interference, counts 4, 6, and 7:                                                          
                        Count 4:  Isolated antibody that specifically binds to a reversible tyrosine                                     
                        phosphorylation site of a reversibly phosphorylated protein in its phosphorylated                                
                        isoform and does not bind to the non-phosphorylated isoform of said protein, nor                                 
                        to proteins other than said protein.                                                                             
                        Count 6:  Isolated antibody that specifically binds to a reversible phosphorylation                              
                        site of the c-erbB-2 receptor in its active form and does not bind to the inactive                               
                        form of said c-erbB-2 receptor, nor to proteins other than said c-erbB-2 receptor.                               
                        Count 7:  Isolated antibody that specifically binds to a reversible serine or                                    
                        threonine phosphorylation site of a reversibly phosphorylated protein in its                                     
                        phosphorylated isoform and does not bind to the non-phosphorylated isoform of                                    
                        said protein, nor to proteins other than said protein.                                                           
        [2]     The claims corresponding to these counts1 are:                                                                           
                               Total claims           Count 4            Count 6           Count 7       Not involved                    
                 Laudano 38-44 and 47-69 38, 39, 47-53, 59-            38-41, 47-55,    42, 43, 47, 51,                                  
                                                 64, 66, 67, and 69      and 59-69        56, and 57       44 and 58                     
                                                 1-6, 8, 10-12, 14,    1-6, 8, 10, 13,                                                   
                  DFCI             1-33            18, 20-28, and      14, 16-18, 20-   1, 7, 9, and 29    15 and 19                     
                                                       30-32           28, 30 and 33                                                     

        [3]     The parties also refer to two non-existent counts, counts 3 and 5, for purposes of illustration, but                     
                acknowledge that these counts are not really counts in this interference (Paper 27 at Fact 1 and                         
                n.1):                                                                                                                    
                        Count 3:  Isolated antiphosphopeptide antibodies that specifically bind to a                                     
                        protein containing said phosphopeptide, but not specific for the corresponding                                   


                        1  A claim can correspond to more than one count if the claim is broad enough to have been anticipated or        
                rendered obvious by the separate inventions described in more than one count.                                            





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