Ex Parte SMITH - Page 13



              Appeal No. 2002-2209                                                              Page 13                
              Application No. 08/137,168                                                                               

              As such, the Theakston article is less than an independent review of the single data                     
              point and any interpretation and extension of that single data point must be viewed in                   
              the context of appellant’s co-authorship of the article.  Furthermore, Theakston itself                  
              sets forth the reason why the single data point should not be extended in the manner                     
              appellant desires.  Theakston states that the so-called dilution effect which appellant                  
              argues teaches away from mixing monovalent serums as required by claim 37 on                             
              appeal to produce a polyvalent sera is minimized because many venoms are highly                          
              cross reactive.  Thus, experimental work relied upon to establish that mixed monovalent                  
              sera is more effective than polyvalent sera must be evaluated in light of the specific                   
              snake venoms used and their cross reactivity.  The greater the cross reactivity, the less                
              the so-called dilution effect would be expected to occur which undercuts appellant’s                     
              argument in regard to unexpected results.  Clearly, comparing the vast scope of claim                    
              37 on appeal with the single data point relied upon by appellant based upon four related                 
              rattlesnakes, we agree with the examiner’s conclusion that the proffered data is not                     
              commensurate in scope with claim 37.                                                                     
                                                      Summary                                                          
                     As explained above, we have decided all four of the pending rejections based                      
              upon the patentability of claim 37.  Having found that claim 37 lacks novelty and that                   
              examiner’s case of prima facie obviousness stands unrebutted, we affirm all four of the                  
              examiner’s rejections.                                                                                   










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