Appeal No. 2003-1103 Page 3 Application No. 09/212,029 established. Id., page 3. “PCR amplification has been applied to the diagnosis of genetic disorders . . ., the detection of nucleic acid sequences of pathogenic organisms in clinical samples . . ., the genetic identification of forensic samples, e.g. sperm . . ., the analysis of mutations in activated oncogenes . . . and in many aspects of molecular cloning.” Id., page 4. The invention: provide[s] analytical systems with optimal reaction environments that can analyze microvolumes of sample, detect very low concentrations of a polynucleotide, and produce analytical results rapidly[,] . . . provide[s] easily mass produced, disposable, small (e.g., less than 1 cc in volume) devices having mesoscale functional elements capable of rapid, automated PCR analyses of a preselected cell or cell-free sample, in a range of applications[, and] . . . provide[s] a family of such devices that individually can be used to implement a range of rapid clinical tests, e.g., tests for viral or bacterial infection, tests for cell culture contaminants, or tests for the presence of recombinant DNA or a gene in a cell, and the like. Id., page 5. Discussion The claims stand or fall together because appellants have not argued to the contrary in either the Appeal Brief or the Reply Brief. Also, because multiple claims have been rejected on the same basis, we have chosen claim 44 as representative of the rejected claims. See 37 CFR § 1.192(c)(7). 1. The rejection under 35 U.S.C. § 102(e). The examiner rejected claims 12-15, 23, 39, 40, and 44-47 as anticipated by Schnipelsky. Examiner’s Answer, page 3. The examiner characterized Schnipelsky as disclosing a device meeting the limitations of the instant claimsPage: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007