Ex Parte WILDING et al - Page 5


               Appeal No. 2003-1103                                                 Page 5                 
               Application No. 09/212,029                                                                  

               “Schnipelsky et al. provides no disclosure which satisfies the claim recitation             
               ‘said flow channel and said reaction chamber having at least one cross-sectional            
               dimension of width or depth which is between about 0.1 to 500 µm.’”  Appeal                 
               Brief, page 11.  Appellants contend that Schnipelsky is silent regarding these              
               dimensions.  Id.  Appellants argue that the dimensions, listed in column 11, lines          
               20-30 of Schnipelsky and noted by the examiner in the final rejection on page 4,            
               are the dimensions of the “materials of construction,” and are “not the dimensions          
               of the flow channel and reaction chamber required in appellants’ claims.”  Appeal           
               Brief, page 12 (emphasis in original).  The focal point of appellants’ argument is          
               that the examiner has “misinterpreted the meaning of ‘thermal path length’” as              
               used by Schnipelsky.  Reply Brief, page 3.  Appellants refer to column 8, lines             
               26-61, where thermal path length is first discussed:                                        
                      Considering first the preferred thermal transfer mechanism, namely                   
                      the passive transfer wall of the compartment, the material of such                   
                      wall is selected to provide a predetermined thermal path length and                  
                      thermal resistance that will provide a high rate of thermal energy                   
                      transfer.  Most preferably, such path length is no greater than about                
                      0.3 mm . . . .   These properties are readily achieved by constructing               
                      the thermal transfer wall out of a plastic, or a laminate of plastic and             
                      metal such as aluminum that is about 0.05 mm thick.                                  
               Reply Brief, page 4 (quoting Schnipelsky, column 8, lines 26-37) (emphasis                  
               added in Reply Brief).  Based on this disclosure, appellants contend that the term          
               “thermal path length” refers to the “material of construction used for the thermal          
               transfer wall . . . not . . . the internal dimensions of the reaction compartment, or a     
               flow channel or any other void space within the device.”  Reply Brief, page 5.              








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