Appeal No. 2003-1167 Page 4 Application No. 09/195,340 opinion that the examiner failed to demonstrate that Hubbell discloses each and every limitation of the claimed invention. Accordingly, we reverse the rejection of claims 6, 14, 18, 19 and 24 under 35 U.S.C. § 102(e) as being anticipated by Hubbell. THE REJECTION UNDER 35 U.S.C. § 103: As discussed above, the examiner recognizes (Answer, page 6) that Hubbell does not teach vascularization, or the active agents of the claimed invention. Accordingly, Hubbell alone is not sufficient to establish a prima facie case of obviousness. However, the examiner asserts (id.), “[o]ne skilled in the art would be motivated further to include [the] instant active agent since the references of Sierra, Hunziker and Marx teach the deliver[y] of these agents at the site based on the same principle, that is ‘polymerization at the site’….” With emphasis on Hunziker, the examiner asserts (Answer, page 7), Hunziker clearly states that the growth factor, Fibroblast growth factor is involved in the growth of vascular endothelial cells. Applicant’s [sic] arguments that Hunziker is not directed to vascularization are not found to be persuasive since Hunziker teaches the application of the composition after surgery and naturally the tissue healing involves vascularizaiton. However, Hunziker is directed to repairing defects in cartilage, and appellants point out (Brief, page 11) that “cartilage is avascular ([Hunziker], column 1, lines 37-38).” Therefore, appellants’ argue (id.), “Hunziker clearly fails to disclose a treatment which promotes vascularization or revascularization.” Appellants find the same flaw in the examiner’s reliance on Sierra and Marx, which according to appellants “are directed to repairing avascular cartilage.” Brief, page 12.Page: Previous 1 2 3 4 5 6 7 NextLast modified: November 3, 2007