Ex Parte Reeves et al - Page 2




              Appeal No. 2003-1416                                                                Page 2               
              Application No. 09/819,549                                                                               


                                                  INTRODUCTION                                                         
                     All the claims are rejected as unpatentable.  As evidence of unpatentability, the Examiner        
              relies upon the following prior art references:                                                          
              Ray W. Gifford, Jr., Management of Isolated Systolic Hypertension in the Elderly, 34 J. of the           
              Am. Geriatrics Soc’y 106 (1986) (EMBASE 969).                                                            
              A New Class of Potent Antihypertensive Agents: Especially Systolic Pressure is Significantly             
              Reduced, MMW Fortschritte Der Medizin, vol. 141, no. 47 at 8 (Nov. 25, 1999) (MEDLINE                    
              858).1                                                                                                   
              Vasopeptidase-Inhibitor: Omapatrilat in Systolic Hypertension, Deutsche Apotheker Zeitung,               
              vol. 140, no. 8, Feb. 24, 2000 at 36 (EMBASE 767).2                                                      


                     Claims 14-24 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over                   
              EMBASE 767 or MEDLINE 858 alone or in view of EMBASE 969.                                                
                     Appellants indicate that claims 14-24 stand or fall together.  We select claim 14, the only       
              independent claim, to represent the issues on appeal.  Claim 14 reads as follows:                        
                     14.  A method of treating isolated systolic hypertension in a human patient comprising            
              administering to said patient an effective amount of a vasopeptidase inhibitor.                          


                     Because we agree with the Examiner's conclusion of unpatentability in view of the prior           
              art, we affirm the Examiner's decision refusing to allow the claims.  However, since our rationale       


                     1We rely upon and cite to the English translation of record.                                      
                     2We rely upon and cite to the English translation of record.                                      







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