Ex Parte HASEBE et al - Page 6


                     Appeal No.  2003-1428                                                                       Page 6                        
                     Application No.  09/468,777                                                                                               

                     comprising “an amphipathic lipid having an average particle size of 0.5 to 150 µm                                         
                     as a solid particulate,” see claim 19.                                                                                    
                             As pointed out by appellants, Nakamura teaches that the lipid (component                                          
                     A) and surfactant (components B and/or C) are melted together, after which the                                            
                     aqueous phase is added.  According to the reference, “[a]n anisotropic liquid                                             
                     crystal phase is formed which, after cooling to room temperature a lipid                                                  
                     microdispersion is obtained which is suitable for cosmetic composition                                                    
                     application.”  Nakamura, page 3, lines 18-20.  Similarly, Dubief teaches that:                                            
                                     The cationic dispersions . . . can be prepared by forming a                                               
                             paste of the cationic surface-active agent and of the ceramide,                                                   
                             followed by melting the mixture at a temperature of approximately                                                 
                             80°C. and then adding hot water (80°-90°C.) with vigorous stirring                                                
                             using an Ultraturrax.                                                                                             
                     Dubief, col. 3, lines 38-43.                                                                                              
                             The claim limitation that the lipid is present as a solid particulate requires                                    
                     that the lipid be dispersed in the surfactant, and the aqueous solution, if present,                                      
                     and thus excludes the compositions of Nakamura and Dubief, wherein the lipid                                              
                     and surfactant have been melted together and are present together in the same                                             
                     phase, i.e., an anisotropic crystal phase wherein the lipid is present in                                                 
                     conjunction with the surfactant.                                                                                          
                             We also agree that the combination based on Pillai does not teach a                                               
                     composition, “wherein said amphipathic lipid has an average particle size of 0.5                                          
                     to 150 µm as a solid particulate,” see claim 11, or a composition comprising “an                                          
                     amphipathic lipid having an average particle size of 0.5 to 150 µm as a solid                                             
                     particulate,” see claim 19.                                                                                               





Page:  Previous  1  2  3  4  5  6  7  8  9  Next 

Last modified: November 3, 2007