Appeal No. 2003-1428 Page 6 Application No. 09/468,777 comprising “an amphipathic lipid having an average particle size of 0.5 to 150 µm as a solid particulate,” see claim 19. As pointed out by appellants, Nakamura teaches that the lipid (component A) and surfactant (components B and/or C) are melted together, after which the aqueous phase is added. According to the reference, “[a]n anisotropic liquid crystal phase is formed which, after cooling to room temperature a lipid microdispersion is obtained which is suitable for cosmetic composition application.” Nakamura, page 3, lines 18-20. Similarly, Dubief teaches that: The cationic dispersions . . . can be prepared by forming a paste of the cationic surface-active agent and of the ceramide, followed by melting the mixture at a temperature of approximately 80°C. and then adding hot water (80°-90°C.) with vigorous stirring using an Ultraturrax. Dubief, col. 3, lines 38-43. The claim limitation that the lipid is present as a solid particulate requires that the lipid be dispersed in the surfactant, and the aqueous solution, if present, and thus excludes the compositions of Nakamura and Dubief, wherein the lipid and surfactant have been melted together and are present together in the same phase, i.e., an anisotropic crystal phase wherein the lipid is present in conjunction with the surfactant. We also agree that the combination based on Pillai does not teach a composition, “wherein said amphipathic lipid has an average particle size of 0.5 to 150 µm as a solid particulate,” see claim 11, or a composition comprising “an amphipathic lipid having an average particle size of 0.5 to 150 µm as a solid particulate,” see claim 19.Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007