Ex Parte HASEBE et al - Page 7


                     Appeal No.  2003-1428                                                                       Page 7                        
                     Application No.  09/468,777                                                                                               

                             Pillai teaches a composition comprising:                                                                          
                                     (i) from about 0.000001% to about 10 wt. % of 25-OH-D3;                                                   
                                     (ii) from about 0.0001% to about 50 wt. % of a lipid material                                             
                             selected from the group consisting of ceramides, pseudoceramides,                                                 
                             neoceramides, and mixtures thereof; and                                                                           
                                     (iii) a cosmetically acceptable vehicle for the 25-OH-D3 and                                              
                             the lipid material.                                                                                               
                     Col. 4, lines 27-33.  Pillai also teaches that surfactants may be present in the                                          
                     composition, see Col. 13, lines 45-67, but there is no teaching that the lipid is                                         
                     present as a solid particulate that is dispersed in the surfactant, as required by                                        
                     the claims.  As Vanlerberghe or Young are relied upon to meet the limitation of                                           
                     the average particle size of the lipid of 0.5 to 150 µm, those references do not                                          
                     remedy the deficiencies of Pillai.                                                                                        



























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