Ex Parte VERHEUL-KOOT et al - Page 2



              Appeal No. 2004-0339                                                                Page 2                
              Application No. 09/462,678                                                                                
              Alexander                                 5,053,387                   Oct. 1, 1991                        
              Vester                                    6,203,818                   Mar. 20, 2001                       
              Henningfield et al. (Henningfield)        WO 93/16595                 Sept. 2, 1993                       
                     Claims 1, 2, 4-8, 10-12, 14-18 and 20 stand rejected under 35 U.S.C. § 103 as                      
              unpatentable over Henningfield and Vester, while claims 9 and 19 stand rejected under                     
              35 U.S.C. § 103 as unpatentable over Henningfield, Vester and Alexander.                                  
                     We reverse both of these rejections.                                                               
                                                    DISCUSSION                                                          
                     In its broadest aspect, the claimed invention is directed to a nutritional                         
              composition comprising proteins, carbohydrates and fats, and, in defined ratios, arginine                 
              equivalents, ascorbic acid equivalents, "-tocopherol equivalents (e.g., vitamin E) and                    
              flavenoids (claim 1).1                                                                                    
                     There are two rejections under 35 U.S.C. § 103, and each is founded on the                         
              combination of Henningfield and Vester.  We view the examiner’s proposed combination                      
              of these two references as the dispositive issue in each of the rejections, so we will                    
              discuss the rejections together.                                                                          
                     Henningfield describes a “nutritional product for persons subjected to trauma or                   
              surgery” (page 1) comprising partially digested protein (a certain portion of which is L-                 
              arginine), carbohydrates and fats, as well as various minerals, salts, and vitamins A, B,                 
              C, D and E.  The product has a caloric density of about 1.2 to 1.5 Kcal/mL and a calorie                  
              to nitrogen ratio of about 112:1 to 145:1 and is intended to “replace or maintain the                     
              body’s normal level of nutrients by providing adequate energy substrates, protein, and                    


                     1  Arginine equivalents are “metabolic equivalents of arginine such as ornithine or                
              citrulline” (specification, page 2); ascorbic acid equivalents are “compounds that can be                 
              transformed to ascorbic acid in the body, such as dehydroascorbic acid, ascorbyl                          
              palmitate and other ascorbyl esters” (id., page 3); and "-tocopherol equivalents include                  
              D-$-tocopherol, D-(-tocopherol, D-"-tocotrienol, etc. (id.).                                              

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