Ex Parte THOMAS et al - Page 7


                 Appeal No.  2004-0735                                                         Page 7                  
                 Application No.  08/081,540                                                                           
                 an epitope of the Der p VII protein allergen.  The examiner has identified a                          
                 murine LIF peptide that comprises a 7 amino acid region that corresponds to a 7                       
                 amino acid region in the Der p VII protein allergen.  There is no evidence of                         
                 record that this 7 amino acid region of the Der p VII protein allergen is not an                      
                 epitope as defined in appellants’ claimed invention.  Accordingly, we are not                         
                 persuaded by appellants’ arguments.                                                                   
                 Conclusion:                                                                                           
                        As set forth above, there is no requirement in appellants’ claims that the                     
                 peptide encoded by the claimed nucleic acid is recognized by a T cell or B cell                       
                 receptor specific for the Der p VII protein allergen.  The claims simply require that                 
                 the peptide encoded by the claimed nucleic acid contain an epitope of the Der p                       
                 VII protein allergen.  Accordingly, we are not persuaded by appellants’                               
                 arguments that a T cell or B cell receptor specific for the Der p VII protein                         
                 allergen will not recognize murine LIF protein.                                                       
                        Both the examiner and appellants appreciate that the Der p VII protein                         
                 allergen and the murine LIF protein share 7 amino acids in common.  According                         
                 to the examiner (Answer, page 3), the 7 amino acids common to both the Der p                          
                 VII protein allergen and murine LIF protein, meets the limitation of comprising at                    
                 least one T cell or B cell epitope.  There is no evidence on this record that this 7                  
                 amino acid region of Der p VII is not an epitope of a T cell or B cell receptor                       
                 specific for a Der p VII protein allergen.                                                            
                        For the foregoing reasons we affirm the rejection of claims 47-49 under 35                     
                 U.S.C. § 103 as being unpatentable over Gearing.                                                      







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