Ex Parte Maurin et al - Page 6



                 Appeal No. 2004-0744                                                                                   Page 6                     
                 Application No. 09/671,188                                                                                                        

                 attention to Coffindaffer’s “anti-dandruff shampoos with particulate active agent and                                             
                 cationic polymer.”  The examiner argues that Coffindaffer, like Cardin, discloses an                                              
                 antidandruff shampoo composition for treating the hair and scalp, comprising zinc                                                 
                 pyridinethione in a cosmetically acceptable medium.  See, Coffindaffer, column 11, lines                                          
                 38 through 44:                                                                                                                    
                         Preferred pyridinethione anti-dandruff agents are water insoluble                                                         
                         1-hydroxy-2-pyridinethione salts.  Preferred salts are formed from heavy                                                  
                         metals such as zinc, tin, cadmium, magnesium, aluminum and zirconium.                                                     
                         The most preferred metal herein is zinc.  The most preferred active is the                                                
                         zinc salt of 1-hydroxy-2-pyridinethione, often referred to as zinc                                                        
                         pyridinethione (ZPT).  (Emphasis added).                                                                                  
                 The examiner also points out that Coffindaffer, like Cardin, discloses particulate                                                
                 antidandruff agents.  See Coffindaffer, column 11, lines 9 through 13 (”The particulate                                           
                 anti-dandruff agent [e.g. zinc pyridinethione] has a volume average particle size of from                                         
                 about 0.35 microns to about 5 microns, preferably from about 0.40 microns to about 3                                              
                 microns, more preferably from about 0.45 microns to about 2 microns”); and Cardin,                                                
                 column 6, lines 27 through 34 (“The pyridinethione salts useful herein take the form of                                           
                 water-insoluble flat platelet particles which have a mean sphericity of less than about                                           
                 0.65, preferably from about 0.20 to about 0.54, and a median particle size of from about                                          
                 2 µ to about 15 µ, preferably from about 5 µ to about 9 µ, the particle size being                                                
                 expressed as the median equivalent diameter of a sphere of equal volume”).  According                                             
                 to the examiner, it would have been obvious to a person having ordinary skill in the art                                          
                 to modify Cardin’s antidandruff shampoo composition, per the teachings of Coffindaffer,                                           
                 by adding a stabilizing agent for the zinc pyridinethione antidandruff agent where the                                            
                 stabilizing agent is a soluble cationic polymer.  See Coffindaffer’s abstract; and see                                            





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