Ex Parte Griffiths - Page 1



                         The opinion in support of the decision being entered today was not written            
                                for publication and is not binding precedent of the Board.                     
                       UNITED STATES PATENT AND TRADEMARK OFFICE                                               
                                                __________                                                     

                            BEFORE THE BOARD OF PATENT APPEALS                                                 
                                          AND INTERFERENCES                                                    
                                                 __________                                                    
                                        Ex parte GARY L. GRIFFITHS                                             
                                                ___________                                                    
                                            Appeal No. 2004-1660                                               
                                          Application No. 10/071,247                                           
                                                 __________                                                    
                                          HEARD: December 9, 2004                                              
                                                 __________                                                    
             Before WILLIAM F. SMITH, SCHEINER and GRIMES, Administrative Patent Judges.                       
             SCHEINER, Administrative Patent Judge.                                                            
                                           DECISION ON APPEAL                                                  
                   This is a decision on appeal under 35 U.S.C. § 134 from the final rejection of              
             claims 9-12 and 16-20.  Claims 13-15, also pending, have been objected to.                        
                   Claim 9 is representative:                                                                  
                   9.  A method for detecting a tissue comprising:                                             
                   (a) administering to a patient a bispecific antibody or antibody fragment                   
             comprising an arm that is specific to a target tissue of the patient and another arm that         
             is specific to an F-18-labeled peptide or a low molecular weight hapten conjugated to             
             the F-18-labeled peptide; and allowing the bispecific antibody or antibody fragment to            
             bind to the target tissue, and the non-targeted bispecific antibody or antibody fragment          
             to clear;                                                                                         
                   (b) administering the F-18-labeled peptide or the hapten conjugate thereof to the           
             patient, and allowing the F-18-labeled peptide or the hapten conjugate thereof to bind to         
             the bispecific antibody or the antibody fragment, and the unbound F-18-labeled peptide            
             or hapten conjugate thereof to clear; and                                                         
                   (c) detecting the F-18-labeled peptide, thereby detecting the target tissue.                
                   Claims 9-12 and 16-20 stand rejected under 35 U.S.C. § 112, first paragraph, as             
             lacking both enablement and adequate written description.  We will reverse both of                
             these rejections.                                                                                 
                                               BACKGROUND                                                      


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