Ex Parte Griffiths - Page 5



             Appeal No. 2004-1660                                                          Page 5              
             Application No. 10/071,247                                                                        
             inventor possessed the invention at the time of the original filing.  See Vas-Cath Inc. v.        
             Mahurkar, 935 F.2d 1555, 1561, 19 USPQ2d 1111, 1115 (CAFC 1991) (“Adequate                        
             description of the invention guards against the inventor’s overreaching by insisting that         
             he recount his invention in such detail that his future claims can be determined to be            
             encompassed within his original creation”).  Stated differently, applicant must convey            
             with reasonable clarity to those skilled in the art that, as of the filing date sought, he or     
             she was in possession of the invention.  “The written description requirement does not            
             require the applicant ‘to describe exactly the subject matter claimed, [instead] the              
             description must clearly allow persons of ordinary skill in the art to recognize that             
             [applicant] invented what is claimed.’” Union Oil Co. of Cal. V. Atlantic Richfield Co., 208      
             F.3d 989, 997, 54 USPQ2d 1227, 1232 (Fed. Cir. 2000) (citation omitted).                          
                   The examiner notes that the specification discloses “only three F-18-labeled                
             peptides, [and] there is a lack of a written description of all additional F-18-labeled           
             peptide[s]    . . . , let alone all bispecific antibodies that bind[ ] to all tissue[s] and all F-
             18-labeled peptide[s] for a method for detecting a tissue by positron emission                    
             tomography” (Answer, page 7).  The examiner believes that “[o]ne of skill in the art              
             would reasonably conclude that the disclosure fails to provide a representative number            
             of species to describe the genus[,] [t]hus, Applicant was not in possession of the                
             claimed genus” (Answer, pages 7-8).                                                               
                   We disagree.  There is no dispute that peptide:antibody binding pairs, tissue               
             marker:antibody binding pairs, and bispecific antibodies are all well-known in the art.  In       
             our view, one of ordinary skill in the art would readily understand that appellant, in            
             describing a method of making and using three specific F-18-labeled peptides, and a               





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