Appeal No. 2004-1935 Page 3
Application No. 09/308,403
broader sense to include the case where viscous solutions are produced rather than
true gels.” Page 4.
“WO 93/10158 describes oxidative gelation of hemicellulosic material using an
oxidizing system comprising a peroxide (such as hydrogen peroxide) and an oxygenase
(such as a peroxidase). However, hydrogen peroxide is inconvenient as a reagent in
industrial-scale processes, and is potentially dangerous.” Page 5.1
The specification discloses a method of oxidative gelation of hemicellulosic
materials using a combination of a peroxidase enzyme and an oxidase enzyme. See,
e.g., page 12: “[T]he invention contemplates a process for effecting oxidative gelation
of a hemicellulosic material comprising the step of promoting the generation of
hydrogen peroxide in situ by redox enzymes. The redox enzymes preferably comprise
an oxidase (e.g., glucose oxidase) and a peroxidase (e.g., horse radish peroxidase),
which are preferably present as supplements in the hemicellulosic material.” See also
page 9: “The material of the invention may further compris[e] an oxidase substrate (e.g.
glucose) supplement. If glucose is used, then this has the ancillary advantage of acting
as a dispersant.”
The specification discloses that the resulting gels or viscous liquids “find a variety
of applications [in] various therapeutic, surgical, prophylactic, diagnostic and cosmetic
(e.g. skin care) applications.” Page 13.
1 WO 93/10158, cited in the specification, is the PCT parent application of the Greenshields patent that is
relied on by the examiner.
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