Ex Parte VOUTE et al - Page 4


               Appeal No. 2005-0209                                                                                                  
               Application 09/274,014                                                                                                

               1555,              35 USPQ2d 1801, 1802 (Fed. Cir. 1995) (“The claimed composition is defined as                      
               comprising - meaning containing at least - five specific ingredients.”); In re Baxter, 656 F.2d                       
               679, 686-87,    210 USPQ 795, 802-03 (CCPA 1981) (“As long as one of the monomers in the                              
               reaction is propylene, any other monomer may be present, because the term ‘comprises’ permits                         
               the inclusion of other steps, elements, or materials.”).                                                              
                       We note here that contrary to appellants’ arguments (brief, e.g., pages 14-15; reply brief,                   
               pages 2-3), we find no limitation in any of appealed claims 1, 2, 7 and 11 which precludes                            
               interaction with macromolecules from occurring in or on the interactive polymer network                               
               occupying the pores of the mineral oxide matrix in addition to the interaction with                                   
               macromolecules occurring in and on the interactive polymer network coated on at least a part of                       
               the surface of the mineral oxide matrix.                                                                              
                       Appellants raise several issues with respect to the examiner’s findings that the teachings                    
               of Girot alone satisfies the pore volume of the mineral oxide matrix requirements of claims 1 and                     
               7 without regard to the mineral oxide employed, and particularly when combined with Davis                             
               with respect to zirconium oxide, as well as alone satisfies the requirement of claim 1 that the                       
               interactive polymer matrix fills the pores and coats the surface of the mineral oxide matrix along                    
               with the further requirement of claim 11 that the interactive polymer network includes a                              
               polysaccharide.                                                                                                       
                       Considering first the interactive polymer network requirement, appellants submit that in                      
               Girot, “molecules diffuse into a polymeric lattice contained within pores” which does not                             
               suggest “interaction on the external surface area of the support” as required by the claims, citing                   
               col. 19, l. 32, to col. 20, l. 16, and FIG. 5 of the reference (brief, pages 14-15; reply brief, pages                
               2-3).  The examiner finds that Girot teaches “an interactive polymer network which fills the                          
               pores and is coated on the surface of the mineral oxide matrix . . . so that subsequent interaction                   
               with macromolecules occurs on the external surface of the support,” citing, among others, col. 5,                     
               ll. 3-62, and col. 6, ll. 31-35 (answer, pages 3-4 and 5).                                                            
                       We agree with the examiner.  Girot describes the porous solid matrix, including porous                        
               mineral oxide matrices, as having innate groups on the interior and exterior surfaces that can                        
               enter into undesirable interactions with biological molecules, and would have taught forming a                        
               polymer network by contacting “the surfaces of the matrix” with a “passivation mixture,”                              

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