Ex Parte VOUTE et al - Page 7


               Appeal No. 2005-0209                                                                                                  
               Application 09/274,014                                                                                                

               endpoint of Girot’s range” (reply brief, page 2).  Appellants further contend that even if “Girot                     
               discloses supports with a range of porosities that abuts the porosity range of the claimed supports                   
               . . . a prima facie case of obviousness can be overcome by showing the recited range achieves                         
               unexpected results,” citing In re Woodruff, 919 F.2d 1575, 1577-78, 16 USPQ2d 1934, 1936-37                           
               (Fed. Cir. 1990) (reply brief, page 2).  In this respect, appellants allege that the interactive                      
               polymer network is only in the pores of the supports of Girot, and not on the external surface of                     
               the support as claimed (id.), and that the “design and mechanism of the inventive supports are                        
               substantially different from those disclosed by Girot,” noting a number of characteristics of the                     
               interactive polymer network of the reference and certain characteristics of the supports in the                       
               Girot Examples (id., pages 2-3).  Thus, appellants contend that “[i]n contrast to Girot’s supports,                   
               . . . the inventive supports exhibit high density, low porosity, and high external surface area,”                     
               arguing that rapid separation of large macromolecules from smaller molecules is achieved where                        
               “the large pore volumes described by Girot are not useful for this purpose” (id., pages 2-3).                         
                       Appellants further submit that the combination of Girot and Davis would not have                              
               suggested a porosity of less than 30% because “this would be contrary to Girot’s purpose” of                          
               providing an interactive polymer network in the pores,” rendering “Girot unsuitable for its                           
               intended purpose” (brief, pages 15-16).  The examiner notes that appellants offer “no evidence or                     
               reasoning to support this” position (answer, page 11).  Appellants then submit that the                               
               examiner’s position that motivation to combine is provided by the disclosure in Girot that                            
               zirconium oxide can be a porous mineral oxide solid support (answer, pages 5 and 6) is                                
               untenable because there is “no objective evidence of record that an artisan would have been                           
               motivated to combine the chromatographical supports of Girot with the teachings of Davis,                             
               which disclosed methods of fabricating sintered zirconium ceramics for use as . . . catalyst                          
               supports” (reply brief, page 5).  Appellants further contend that the chromatographic supports of                     
               Girot possess “high sorptive capacity and high porosity” and are unrelated to the catalyst                            
               supports of Davis, and thus, the combination would not have “implicated” the claimed supports                         
               with a pore volume of less than 30% to one of ordinary skill in the art (id., pages 5-6).                             
                       Appellants would have us focus on Girot’s preferred porous volume range of 0.8 to 1.2                         
               cm3/gr of solid material even though as the examiner points out, the reference discloses that the                     
               typical range is from about 0.2 to about 2 cm3/gram (Girot, col. 8, ll. 40-44 and 53-55; answer,                      

                                                                - 7 -                                                                



Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  12  13  Next 

Last modified: November 3, 2007