Ex Parte Lind et al - Page 4


                 Appeal No.  2005-0792                                                         Page 4                  
                 Application No.  09/750,373                                                                           
                        post-traumatic-stress disorder, depression, bipolar disorder,                                  
                        delirium, dementia, severe mental retardation; dyskinesias, such as                            
                        Huntington’s disease or Tourette’s Syndrome; attention disorders                               
                        including ADD and ADHD, and degenerative disorders such as                                     
                        Parkinson’s, Alzheimer’s; movement disorders, including ataxias,                               
                        supranuclear palsy, etc.); among others.                                                       
                 According to the specification (page 14), the claimed nucleic acid molecule is                        
                        useful for recombinantly expressing the receptor and also for                                  
                        detecting expression of the receptor in cells … in the design of                               
                        antisense and other molecules for the suppression of the                                       
                        expression of nGPCR-[1007] in a cultured cell, a tissue, or an                                 
                        animal; for therapeutic purposes; or to provide a model for diseases                           
                        or conditions characterized by aberrant nGPCR-[1007] expression.                               
                 In addition, the specification discloses (page 17), “[p]olynucleotides of the                         
                 invention may also provide a basis for diagnostic methods useful for identifying a                    
                 genetic alteration(s) in a nGPCR-x locus that underlies a disease state or states,                    
                 which information is useful both for diagnosis and for selection of therapeutic                       
                 strategies.”                                                                                          
                                                    DISCUSSION                                                         
                        The examiner rejected all of the claims as lacking patentable utility.3  The                   
                 examiner bears the initial burden of showing that a claimed invention lacks                           









                                                                                                                       
                 3 The examiner rejected the claims under 35 U.S.C. § 101 and 35 U.S.C. § 112, first paragraph.        
                 However the rejection for nonenablement was presented simply as a corollary of the finding of         
                 lack of utility.  See Answer, page 5.  Therefore, although we discuss only the § 101 rejection, our   
                 conclusion also applies to the § 112 rejection.                                                       





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