Ex Parte Michelson - Page 5



          Appeal No. 2005-1002                                                        
          Application No. 09/991,247                                                  

          osteoinductive, osteogenic, or other fusion enhancing material”             
          (column 5, line 66, through column 6, line 5).                              
               To remedy the foregoing deficiency in Michelson ‘973, the              
          examiner turns to Boyce ‘187.                                               
               Boyce ‘187 discloses a number of osteoimplants including a             
          cylinder or dowel 70 similar in type to those disclosed by                  
          Michelson ‘973 for insertion between adjacent vertebrae (see                
          Figures 1d and 2b; column 1, lines 26 through 30; and column 14,            
          line 6, through column 15, line 5).  To manufacture the implants,           
          Boyce ‘187 expressly contemplates a machinable composite of                 
          cortical bone particles (see column 4, lines 26 through 52) and             
          biocompatible components such as bioabsorbable materials (see               
          column 7, line 55, through column 12, line 10).  Boyce ‘187 lists           
          a number of advantages afforded by such osteoimplants including             
          load-bearing strength, the presence of pores which permit                   
          revascularization and incorporation by the host, an osteogenic              
          quality which promotes new host bone tissue formation, and easy             
          fabrication of osteoimplants having different sizes and/or shapes           
          (see, for example, column 2, lines 7 through 33).                           
               The test for obviousness is not whether the features of a              
          secondary reference may be bodily incorporated into the structure           
          of the primary reference; nor is it that the claimed invention              
          must be expressly suggested in any one or all of the references.            
          Rather, the test is what the combined teachings of the references           
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