Appeal No. 2005-1169 Page 2
Application No. 09/900,063
assaying for the presence of a genotype in the prolactin receptor gene
sequence as set forth in SEQ ID NO: 3 or a region thereof in said sample,
wherein said genotype is comprised of a polymorphism in the prolactin
receptor gene associated with increased litter size; and
characterizing said animal.
27. A method for identifying a genetic marker for litter size in animals
comprising the steps of:
breeding male and female animals of the same breed or breed cross or
derived from similar genetic lineages;
determining the number of offspring produced by each female animal;
determining the polymorphism in the prolactin receptor gene as set forth in
SEQ ID NO: 3 of each female animal; and
associating the number of offspring produced by each female animal with
said polymorphism thereby identifying a polymorphism for pig2 litter size.
36. A method for screening pigs to determine those more likely to
produce larger litters, and/or those less likely to produce larger litters,
which method comprises of the steps:
determining the alleles of prolactin receptor present in a pig having SEQ
ID NO:3;
determining the alleles of other markers for genes known to affect litter
size; and
selecting for animals with favorable combinations of alleles and against
those carrying unfavorable combinations.
54. A method for identifying a marker correlated with litter size
comprising the steps of:
obtaining a sample of genetic material from an animal, said sample
comprising a prolactin receptor gene as set forth in SEQ ID NO:3;
2 The recitation of “pig” appears to lack antecedent basis in the claim, as the rest of the claim
refers to “animal.” Upon return of the application, the examiner should address this discrepancy
in the claim.
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