Ex Parte Rothschild et al - Page 10


                Appeal No. 2005-1169                                                   Page 10                  
                Application No. 09/900,063                                                                      

                       Claims 27 and 54, however, are drawn to methods for identifying a marker                 
                correlated with litter size.  The examiner does not address in the rejection how                
                such screening methods to identify a polymorphism associated with litter size are               
                not supported by an adequate written description, and we are thus compelled to                  
                reverse the written description rejection as to claims 27 and 54 and the claims                 
                dependent thereon, i.e., claims 28, 29 and 55.                                                  
                       Claims 1-3, 8-11, 16, 17, 19, 20, 26-29, 36-38, 54 and 55 stand rejected                 
                under 35 U.S.C. § 112, first paragraph, on the grounds that the specification,                  
                while being enabling for some polymorphisms in the porcine prolactin receptor                   
                such as the Alu polymorphism, does not reasonably provide enablement for all                    
                polymorphisms including the Msel polymorphism.                                                  
                       The examiner states in the conclusion to the rejection, “the specification               
                does not provide guidance to overcome art and specification recognized                          
                problems in the use of polymorphisms as prognostic of litter size as broadly                    
                claimed.”  Examiner’s Answer, page 9 (emphasis in original).  As we have noted                  
                above, the examiner has focused the rejection on the subject matter of claims 1                 
                and 36 and the claims dependent thereon.                                                        
                       Therefore, as the examiner has not addressed the subject matter of claims                
                27, 28, 29, 54 and 55, i.e., methods for identifying genetic markers associated                 
                with litter size, we are compelled to reverse the enablement rejection as to those              
                claims.  Moreover, because we affirmed the written description                                  









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