Ex Parte LI et al - Page 2






              48.  The method of claim 47, wherein the disease or condition is ischemia.                               
              49.  The method of claim 47, wherein the disease or condition is reperfusion injury.                     
                     The prior art references cited by the examiner are:                                               
              Wang    1077644 CH    Oct. 27, 1993                                                                      
              Ning    1113711 CH    Dec. 27, 1995                                                                      
              Tanuma 1   3-205402 JP    Sept. 6, 1991                                                                  
              Tanuma 2   4-13684 JP     Jan. 17, 1992                                                                  

              Wen et al. (Wen), “Ginseng root prevents learning disability and neuronal loss in gerbils                
              with 5 minute forebrain ischemia,” Acta Neuropathol., Vol. 91, pp. 15-22 (1996).                         
              Kim et al. (Kim), “Effects of Ginseng on Global Myocardial Ischemia and Reperfusion in                   
              the Rat Heart,” J. Pharm Soc. Korea, Vol. 32, No. 1, pp. 70-79 (1988) [BIOSIS Abstract                   
              Only].                                                                                                   

              Grounds of Rejection                                                                                     
                     I. Claims 46-49 stand rejected under 35 U.S.C. §112, first paragraph for lack of                  
              enablement.                                                                                              
                     II.  Claims 46-49 stand rejected under 35 U.S.C. §102(b) over Wang, Ning and                      
              Tanuma 1 and 2.                                                                                          
                     III.  Claims 46-49 stand rejected under 35 U.S.C. §103(a) over Wang, Ning,                        
              Tanuma 1 and 2 in further view of Kim and Wen.                                                           
                     We reverse rejections I-III.                                                                      














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