Ex Parte Bryan - Page 6


               Appeal No. 2006-0381                                                                       Page 6                  
               Application No. 09/729,133                                                                                         

               “replacing the entire chemiluminescent system (i.e., all of the oxalate diester, the                               
               peroxide and the fluorescer in the preferred embodiment of Halbritter) used with the                               
               bioluminescent fluorescent protein of Prasher.”  Examiner’s Answer, page 15.  Thus,                                
               any potential incompatibility between the A. victoria GFP and the components of                                    
               Halbritter’s system would not lead persons skilled in the art away from combining the                              
               cited references.                                                                                                  
                                                           Summary                                                                
                      The examiner has made out a prima facie case of obviousness, which Appellant                                
               has not rebutted.  We therefore affirm the rejection of claim 5.  Claims 1-3 and 8-14 fall                         
               with claim 5.                                                                                                      


                                                          AFFIRMED                                                                



                                      Toni R. Scheiner   )                                                                        
                                      Administrative Patent Judge )                                                               
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                                                                            ) BOARD OF PATENT                                     
                                      Eric Grimes    )                                                                            
                                      Administrative Patent Judge )   APPEALS AND                                                 
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                                                                            ) INTERFERENCES                                       
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                                      Lora M. Green   )                                                                           
                                      Administrative Patent Judge )                                                               











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