Ex Parte H. Shih - Page 10


               Appeal No. 2006-0650                                                                      Page 10                  
               Application No. 10/007,613                                                                                         

               described by Huth as “suitable proteolytic enzymes” in for cleaning and disinfection.                              
               Huth, column 15, lines 13-15.                                                                                      
                      We agree with the examiner that the skilled worker would have been motivated to                             
               have utilized the particular keratinase disclosed in Shih in view of Huth’s suggestion that                        
               this class of enzymes is useful for disinfection purposes and the skilled worker’s                                 
               reasonable expectation that it would have similar properties as being a member of the                              
               same enzyme class.  See, e.g., Dillon, 919 F.2d at 693, 696, 16 USPQ2d at 1901,                                    
               1904.  Appellant did not separately argue this limitation, and there was no evidence of                            
               record that one type of keratinase is any better than another.                                                     
                                                  New Grounds of Rejection                                                        
                      Under the provisions of 37 C.F.R. § 41.50(b), we enter the following new grounds                            
               of rejection.                                                                                                      
               Indefiniteness, 35 U.S.C. § 112, second paragraph                                                                  
                      Claims 39-51, 53-55, 63, 71, 73, 74, and 80 are rejected under § 112, second                                
               paragraph, as being indefinite.                                                                                    
                      The independent claims are reproduced below:                                                                
                      39.  A system comprising:                                                                                   
                      (a) one or more articles susceptible to contamination by infectious prion                                   
                      protein;                                                                                                    
                      (b) means for heating said articles;                                                                        
                      (c) a proteolytic enzyme selected from the group consisting of keratinases                                  
                      and subtilisins; and                                                                                        
                      (d) means for exposing said articles to said proteolytic enzyme;                                            
                      wherein said one or more articles are characterized by a first elevated                                     
                      temperature of at least 40°C and not more than 150°C during a first                                         
                      duration, wherein said articles are characterized by a second elevated                                      

                                                                                                                                  
               3 Shih et al. (Shih), U.S. Pat. No. 5,171,682, issued Dec. 15, 1992.                                               





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