Ex Parte Nair et al - Page 16


               Appeal No. 2006-1245                                                                        Page 16                   
               Application No. 10/294,106                                                                                            

               combined with the very low threshold concentration required to induce inhibition, we find                             
               that Thakur inherently provides the claimed withanolides to a mammal in amounts                                       
               effective to selectively inhibit COX-2.  Thakur therefore anticipates claims 1, 3, 5, and                             
               15.                                                                                                                   
                       To summarize, “a prior art reference may anticipate when the claim limitations                                
               not expressly found in that reference are nonetheless inherent in it.”  In re Cruciferous                             
               Sprout Litigation, 301 F.3d 1343, 1349, 64 USPQ2d 1202, 1206 (Fed. Cir.  2002).                                       
               Moreover, “the discovery of a previously unappreciated property of a prior art                                        
               composition, or of a scientific explanation for the prior art’s functioning, does not render                          
               the old composition patentably new to the discoverer. . . .  This same reasoning holds                                
               true when it is not a property, but an ingredient, which is inherently contained in the prior                         
               art.”  Atlas Powder, 190 F.3d at 1347, 51 USPQ2d at 1947 (emphasis added).  Thus,                                     
               the fact that Appellants may have recognized novel compounds within prior art W.                                      
               somnifera compositions cannot render methods of using those compositions patentable,                                  
               when the prior art discloses using compositions encompassed by the claims according                                   
               to the claimed steps.  See Cruciferous Sprout, 301 F.3d 1343, 64 USPQ2d 1202 (claims                                  
               to therapeutic methods of administering sprout compositions held anticipated due to                                   
               inherent presence of claimed therapeutic agent therein).                                                              
                       Lastly, we note that “where the Patent Office has reason to believe that a                                    
               functional limitation asserted to be critical for establishing novelty in the claimed subject                         
               matter may, in fact, be an inherent characteristic of the prior art, it possesses the                                 
               authority to require the applicant to prove that the subject matter shown to be in the                                
               prior art does not possess the characteristic relied on.”  In re Swinehart, 439 F.2d 210,                             





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