Appeal No. 2006-1270 Page 2 Application No. 10/222,614 122. The cell of claim 121, wherein the cell is a human cell. 123. The cell of claim 122, wherein the cell is a stem cell. 124. The cell of claim 123, wherein the cell is a hematopoietic stem cell. Claims 123 and 124 stand rejected under 35 U.S.C. § 112, first paragraph, as failing to comply with the enablement requirement. In addition, Claims 114, 116 and 119-122 stand rejected under 35 U.S.C. § 103(a) as being obvious over the combination of Brenneman1 and Chandrasegaran.2 After careful review of the record and consideration of the issues before us, we reverse both rejections. DISCUSSION Claims 123 and 124 stand rejected under 35 U.S.C. § 112, first paragraph, “as failing to comply with the enablement requirement. The claim(s) contains subject matter which was not described in the specification in such a way as to enable one skilled in the art to which it pertains, or with which it is most nearly connected, to make and/or use the invention.” Examiner’s Answer, page 3. 1 Brenneman et al. (Brenneman), “Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases,” PNAS, Vol. 93, pp. 3608-12 (1996). 2 Chandrasegaran, U.S. Pat. No. 5,792,640, issued August 11, 1998.Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007