Ex Parte Buch - Page 1




                         The opinion in support of the decision being entered today was not written           
                                for publication and is not binding precedent of the Board.                    

                       UNITED STATES PATENT AND TRADEMARK OFFICE                                              
                                                 __________                                                   
                            BEFORE THE BOARD OF PATENT APPEALS                                                
                                         AND INTERFERENCES                                                    
                                                 __________                                                   
                                             Ex parte JAN BUCH                                                
                                                 __________                                                   
                                            Appeal No. 2006-1304                                              
                                          Application No. 10/214,058                                          
                                                 __________                                                   
                                             HEARD April 6, 2006                                              
                                                 __________                                                   
            Before SCHEINER, ADAMS, and GRIMES, Administrative Patent Judges.                                 
            GRIMES, Administrative Patent Judge.                                                              

                                           DECISION ON APPEAL                                                 
                   This appeal involves claims to a pharmaceutical composition comprising                     
            atorvastatin and amlodipine.  The examiner has rejected the claims for obviousness.               
            We have jurisdiction under 35 U.S.C. § 134.  Because we conclude that the prior art               
            would have led those skilled in the art to combine atorvastatin and amlodipine in a               
            single composition, we affirm the rejections with respect to all claims except claim 144.         
                                                 Background                                                   
                   “The conversion of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) to                      
            mevalonate is an early and rate-limiting step in the cholesterol biosynthetic pathway.            
            This step is catalyzed by the enzyme HMG-CoA reductase.  Statins inhibit HMG-CoA                  







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