The opinion in support of the decision being entered today was not written for publication and is not binding precedent of the Board. UNITED STATES PATENT AND TRADEMARK OFFICE __________ BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES __________ Ex parte JAN BUCH __________ Appeal No. 2006-1304 Application No. 10/214,058 __________ HEARD April 6, 2006 __________ Before SCHEINER, ADAMS, and GRIMES, Administrative Patent Judges. GRIMES, Administrative Patent Judge. DECISION ON APPEAL This appeal involves claims to a pharmaceutical composition comprising atorvastatin and amlodipine. The examiner has rejected the claims for obviousness. We have jurisdiction under 35 U.S.C. § 134. Because we conclude that the prior art would have led those skilled in the art to combine atorvastatin and amlodipine in a single composition, we affirm the rejections with respect to all claims except claim 144. Background “The conversion of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) to mevalonate is an early and rate-limiting step in the cholesterol biosynthetic pathway. This step is catalyzed by the enzyme HMG-CoA reductase. Statins inhibit HMG-CoAPage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007