Ex Parte Pahl et al - Page 3




              Appeal No. 2006-1391                                                                                        
              Application No. 10/168,806                                                                                  

              van Reis                      5,256,294          Oct. 26, 1993                                              
              Millipore, Catalog on Pellicon® Tangential Flow Filtration Cassettes, March 1999.                           
                     Claims 1-6 stand rejected under 35 U.S.C. § 103(a) as unpatentable over van                          
              Reis (Answer, page 3).  Based on the totality of the record, we affirm the rejection on                     
              appeal.  However, since we advance a rationale significantly different from the examiner                    
              in the Answer, we denominate this “affirmance” as a new ground of rejection pursuant to                     
              the provisions of 37 CFR § 41.50(b)(2004) to allow appellants the option of reopened                        
              prosecution or rehearing.  Our reasons follow.                                                              
              OPINION                                                                                                     
                     The examiner finds that van Reis discloses a cross-flow filter device having                         
              membranes with feed inlets, permeate outlets, and concentrate outlets, where the                            
              membranes have multiple plies or a plurality of two-ply membranes, with pore sizes                          
              decreasing from the feed side ply to the permeate side ply (Answer, page 3).  With                          
              regard to the cassette form of structure, the examiner finds that van Reis teaches use of                   
              Millipore Pellicon ultrafiltration systems, and cites the Millipore catalog as evidence of                  
              this structure (id.; see also pages 7-8).                                                                   
                     The examiner finds that the claims differ from the teachings of van Reis in that                     
              the reference does not teach the ratio of pore size of the front side ply to the backside                   
              ply as 1.3 to 5 (id.).  However, the examiner concludes that it would have been obvious                     
              to one of ordinary skill in the art at the time of appellants’ invention “that such a ratio can             
              be established between the layers (or plies) of membranes ... depending on the particle                     

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