Appeal No. 2006-1460 Application No. 10/033,315 a method of producing a multi-layer laminated substrate. This appealed subject matter is adequately represented by independent claim 1 which reads as follows: 1. A microfluidic substrate assembly comprising: a multi-layer laminated substrate defining at least one fluid inlet port and at least one microscale fluid flow channel within the multi-layer substrate in fluid communication with the inlet port for transport of fluid; and at least one operative component mounted aboard the multi- layer laminated substrate in communication with the microscale fluid flow channel. The references set forth below are relied upon by the examiner as evidence of unpatentability: Wilding et al. (Wilding) 5,928,880 Jul. 27, 1999 Dubrow et al. (Dubrow) 6,475,364 Nov. 5, 2002 Mastrangelo et al. (Mastrangelo) 6,494,433 Dec. 17, 2002 Holl WO 99/60397 Nov. 25, 1999 (published World Intell. Prop. Org. Patent Application) Claims 1-6, 8-19 and 27-35 are rejected under 35 U.S.C. § 102(b) as being anticipated by Holl. Claims 1-6 and 8-12 are rejected under 35 U.S.C. § 102(e) as being anticipated by Dubrow. Claims 1-6 and 8-14 are rejected under 35 U.S.C. § 102(b) as being anticipated by Wilding. 2Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007