Appeal No. 2006-1460 Application No. 10/033,315 that it occurs along the edge portions of Holl’s layers. The appellants’ argument regarding independent method claim 31 corresponds to the claim 27 argument. It follows that this argument is unpersuasive for reasons analogous to those set forth immediately above. In light of the foregoing, it is our determination that the Holl reference evinces a prima facie case of anticipation which the appellants have failed to successfully rebut with argument or evidence to the contrary. We hereby sustain, therefore, the examiner’s Section 102 rejection of claims 1-6, 8-19 and 27-35 as being anticipated by Holl. THE SECTION 102 REJECTION BASED ON DUBROW It is the appellants’ contention that the rejection under consideration is improper because “[t]here is no express disclosure in Dubrow . . . of operative components mounted aboard any such device [i.e., a microfluidic substrate assembly of the type defined by independent claim 1]” (brief, page 19). This is not correct. The examiner has accurately explained in his rebuttal to this contention (and the appellants have not disagreed with this explanation) that Dubrow discloses a microfluidic device having operative components such as an electrical controller and electrodes mounted there aboard as 6Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007