Ex Parte 5578684 et al - Page 28

            Appeal No. 2006-2247                                                                              
            Reexamination Nos. 90/006,554 and 90/006,894                                                      
        1          Here, Witman does not say that an aqueous medium leads to an inoperable                    
        2   process.  Quite the contrary, Witman teaches that the N-oxide product is                          
        3   “somewhat unstable” and therefore the distillation of the water or water and                      
        4   solvent during product recovery must be performed at “low pressure that the N-                    
        5   oxide product is not decomposed.”  (Column 7, lines 39-52.)  Alternatively,                       
        6   Witman teaches that “the N-oxide is best recovered by first converting it to the                  
        7   hydrohalide [which is more stable than the N-oxide], then removing water or water                 
        8   and solvent.”  (Column 7, lines 43-48.)  Thus, Witman expressly discloses                         
        9   solutions to the instability problem, which is to perform low pressure distillation or            
       10   first convert the N-oxide to hydrohalide.  As we discussed above, the appealed                    
       11   claims do not preclude the recovery of N-oxide by first converting the product to                 
       12   the hydrochloride.  The disclosure in Witman is hardly the type of teaching that                  
       13   can reasonably be considered to “teach away.”                                                     
       14          To the extent that the prior art suggests that an aqueous reaction medium is               
       15   inferior to a non-aqueous reaction medium, the patent owner has not satisfactorily                
       16   established any discovery beyond what was known to the art.  Contrary to what the                 
       17   patent owner would have us believe, our reviewing court has explained that the                    
       18   “case law does not require that a particular combination must be the preferred, or                
       19   the most desirable, combination described in the prior art in order to provide the                



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