Ex Parte LOVE et al - Page 14


                Appeal No. 2006-2415                                                                               Page 14                     
                Application No. 09/410,336                                                                                                     

                Yoshimoto.  One skilled in the art would also have reasonably expected that removing                                           
                unbound detecting agent by washing in the manner described by Canto would have                                                 
                removed undesired background signals, thereby increasing the specificity of the assay.                                         
                         Therefore, a preponderance of the evidence supports the examiner’s position                                           
                that Yoshimoto, Schmitt-Willich and Canto would have rendered claim 33 prima facie                                             
                obvious.  Claims 36-39 fall with claim 33.                                                                                     
                3.  Obviousness of claims 34 and 35                                                                                            
                         The examiner has also rejected claims 34 and 35 as obvious in view of                                                 
                Yoshimoto, Schmitt-Willich, and Canto as applied to claims 33 and 36-39, and in further                                        
                view of Barsky.4  Answer, page 9.  Acknowledging that Yoshimoto, Schmitt-Willich and                                           
                Canto do not teach the steps recited in claims 34 and 35,5 the examiner asserts that                                           
                Barsky “teaches delivering a desired diagnostic material through one or more orifices at                                       
                the surface of the breast and into the lumens of the associated breast ducts by                                                
                cannulation or catheterization without piercing or perforating the skin; see entire                                            
                document (e.g., column 6, lines 54-55).”  Id. at page 10.                                                                      
                         The examiner asserts that Barsky would have rendered obvious claim 34’s step                                          
                of delivering the coupled diagnostic compound by non-percutaneous cannulation or                                               
                catheterization of the breast duct because Barsky teaches that the claimed method is “a                                        
                means by which a desired diagnostic material can be instilled through one or more                                              
                                                                                                                                               
                4 Barsky et al., U.S. Patent 6,168,779 B1, issued January 2, 2001 (application filed                                           
                September 16, 1997).                                                                                                           
                5 In the rejection of claims 34 and 35, the examiner incorrectly refers to Schmitt-Willich as “US Patent                       
                6,168,779 B1.”  Answer, page 10, first and second full paragraphs.  It is clear from the context, however,                     
                that the examiner intended to refer to Schmitt-Willich.  The examiner’s discussion on page 10 of the                           
                Answer also refers to U.S. Patent 4,628,027.  However, the examiner has pointed out that citing that                           
                patent “was inadvertent error, as the prior art reference has not been considered, or relied upon in                           
                determining the obviousness of the claimed invention.”  Answer, page 3.                                                        





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