Appeal No. 2006-2415 Page 17 Application No. 09/410,336 We also do not agree with Appellants’ argument (Appeal Brief, pages 18-21) that the cited references fail to provide a sufficiently specific teaching, suggestion or motivation to practice the claimed invention. One of ordinary skill viewing the cited references would have recognized that the claimed combination of steps would have been desirable in a method of detecting cancer cells within the breast ductal network. Thus, one of ordinary skill detecting cancerous lesions according to Yoshimoto would have recognized from Schmitt-Willich the advantage of a more stable detectable agent, as well as the diagnostic advantage of using an antibody specific for breast cancer tumors. The skilled artisan also would have recognized that washing away non- specifically bound detecting agent from the breast ductal network would result in less background signal, thereby increasing assay specificity, much like the washing step in Canto. Lastly, Barsky would have informed the skilled artisan of the advantages of non- percutaneous cannulation. In our view, by looking only to the prior art cited by the examiner, one of ordinary skill would have had incentive to practice the claimed process. Appellants’ additional arguments with respect to this rejection have been adequately addressed above. Therefore, we conclude that a preponderance of the evidence supports the examiner’s position that Yoshimoto, Schmitt-Willich, Canto and Barsky would have rendered claim 34 prima facie obvious. Claim 35 falls with claim 34. Summary We affirm the rejections of claims 33-39 under 35 U.S.C. § 103.Page: Previous 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 NextLast modified: November 3, 2007