Ex Parte Blair et al - Page 7


                Appeal No.  2006-2702                                                   Page 7                
                Application No.  09/881,234                                                                   
                biologists to allow access to the ever-expanding sequence data bases without                  
                requiring copious local data base storage, frequent data base updates, the cost               
                of expensive and sophisticated hardware and software, and the cost and effort of              
                continuous system maintenance . . . .”  The examiner finds, however, that Smith               
                teaches “that the individual WWW server sites scattered throughout the Web                    
                hinders their efficient use . . . .”  Answer, page 9.  According to the examiner (id.),       
                Smith teaches that “the BCM Search Launcher addresses these limitations by                    
                providing an improved interface to simplify access and improve analysis                       
                resources . . . .”                                                                            
                      The examiner finds, however, that Smith “does not describe compressing                  
                and uncompressing data, determining a number of tasks as nN x nM, or looping                  
                processes.”  Answer, page 7.  To make up for this deficiency in Smith, the                    
                examiner relies on Altschul and Reed.                                                         
                      The examiner relies on Altschul to teach that a database can be                         
                compressed “by packing 4 nucleotides into a single byte and using a table to                  
                delimit the boundaries between adjacent sequences . . . .”  Id.  In this regard, the          
                examiner finds (id.), Altschul “describe[s] beginning with a matrix of similarity             
                scores for all possible pairs of residues . . . which represents determining the              
                number of tasks for an entire comparison of two datasets.”  The examiner also                 
                finds (id.), Altschul                                                                         
                      Describe[s] performing BLAST with two random sequences (data                            
                      sets N and M) of lengths m and n in order to determine the                              
                      probability of finding a segment pair with a score greater than S (cut                  
                      off score . . .) where y=Kmn e-λS . . . which represents determination                  
                      of a number of tasks or points in a matrix in a comparison of two                       







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